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Inadequate levels of B12 can lead to conditions like megaloblastic or pernicious anemia, resulting in fatigue, weakness, and pale skin
Homocysteine level is a more direct measure of the function of vitamin B12 and folic acid (compared to red blood cell or serum testing)
A diet rich in animal products, fortified foods, nutritional yeast, and supplements helps maintain adequate B12 levels
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Running both as independent variables within the same 10mg-scale protocol allows precise pathway dissection that would not be possible with a single compound alone